KL-11743 is a potent, orally active, and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90, and 68 nM for GLUT1, GLUT2, GLUT3, and GLUT4, respectively. KL-11743 specifically blocks glucose metabolism. KL-11743 can synergize with electron transport inhibitors to induce cell death.
Molekulargewicht:
522.6
Reinheit:
>99.0%
CAS Nummer:
[1369452-53-8]
Formel:
C30H30N6O3
Target-Kategorie:
GLUT
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