RapaLink-1, CAS [[1887095-82-0]]

Artikelnummer: AMO-M28992
Artikelname: RapaLink-1, CAS [[1887095-82-0]]
Artikelnummer: AMO-M28992
Hersteller Artikelnummer: M28992
Alternativnummer: AMO-M28992-1MG,AMO-M28992-5MG,AMO-M28992-10MG
Hersteller: Abmole Bioscience
Kategorie: Biochemikalien
RapaLink-1, the third-generation bivalent mTOR inhibitor, combines Rapamycin with MLN0128 by an inert chemical linker. RapaLink-1 shows better efficacy than Rapamycin or mTOR kinase inhibitors (TORKi), potently blocking cancer-derived, activating mutants of mTOR. RapaLink-1 can cross the blood-brain barrier. RapaLink-1 binding to FKBP12 results in targeted and durable inhibition of mTORC1. RapaLink-1 plays an antithrombotic role in antiphospholipid syndrome by improving autophagy. Anticancer activity.
Molekulargewicht: 1784.14
Reinheit: 99.0%
CAS Nummer: [1887095-82-0]
Formel: C91H138N12O24
Target-Kategorie: mTOR