TBAJ-587, a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and <0.02 µg/mL in MABA and LORA assay, respectively. TBAJ-587 inhibits hERG channel minimally, attenuates inhibition of the cardiac potassium channel protein coded by the hERG, which is important for cardiac repolarization.
Molekulargewicht:
614.5
Reinheit:
98.0%
CAS Nummer:
[2252316-16-6]
Formel:
C30H33BrFN3O5
Target-Kategorie:
Antibiotic
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