PROTAC PD-1/PD-L1 degrader-1, CAS [[2447066-37-5]]

Produktübersicht

• Artikelname: PROTAC PD-1/PD-L1 degrader-1, CAS [[2447066-37-5]]
• Artikelnummer: AMO-M29649
• Hersteller Artikelnummer: M29649
• Alternativnummer: AMO-M29649-5MG,AMO-M29649-10MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC PD-1/PD-L1 degrader-1, a PD-1/PD-L1 PROTAC based on Cereblon E3 ligand, inhibits PD-1/PD-L1 interaction with an IC50 of 39.2 nM. PROTAC PD-1/PD-L1 degrader-1 significantly restores the immunity repressed in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells. PROTAC PD-1/PD-L1 degrader-1 moderately reduces the protein levels of PD-L1 in a lysosome-dependent manner.

Produkteigenschaften

• Molekulargewicht: 1076.59
• Reinheit: 98.0%
• CAS Nummer: [2447066-37-5]
• Formel: C59H58ClN7O11
• Target-Kategorie: PROTAC