DSP-3235 free base, KGA-3235 free base, GSK-1614235 free base
Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation.
Molekulargewicht:
564.67
Reinheit:
99.0%
CAS Nummer:
[666843-10-3]
Formel:
C28H44N4O8
Target-Kategorie:
SGLT
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