SAR-441566 is an orally active TNF-alpha inhibitor that blocks the interaction of TNFalpha with TNFR1 by distorting the conformation of the soluble TNFalpha trimer and does not affect signaling of TNFalpha bound to cell membranes, and can be used in rheumatoid arthritis-related studies.
Molekulargewicht:
502.52
Reinheit:
>98.0%
CAS Nummer:
[2248726-53-4]
Formel:
C27H24F2N6O2
Target-Kategorie:
TNF Receptor
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