BMH-21, CAS [[896705-16-1]]

Produktübersicht

• Artikelname: BMH-21, CAS [[896705-16-1]]
• Artikelnummer: AMO-M3892
• Hersteller Artikelnummer: M3892
• Alternativnummer: AMO-M3892-1MG,AMO-M3892-5MG,AMO-M3892-10MG,AMO-M3892-25MG,AMO-M3892-50MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien

Produktbeschreibung

BMH-21 is a first-in-class DNA intercalator that binds to high-frequency GC-rich sequences in ribosomal DNA genes and can effectively and rapidly inhibit the transcription of RNA polymerase I (Pol I), leading to degradation of the Pol I catalytic subunit RPA194 and non-phosphorylation of histone H2AX. H2AX is not phosphorylated.BMH-21 has broad and potent antitumor activity in NCI60 cancer cell line and inhibits tumor growth in vivo.

Produkteigenschaften

• Molekulargewicht: 360.41
• Reinheit: >99.0%
• CAS Nummer: [896705-16-1]
• Formel: C21H20N4O2
• Target-Kategorie: DNA/RNA Synthesis