NX-5948, CAS [[2649400-34-8]]

Produktübersicht

• Artikelname: NX-5948, CAS [[2649400-34-8]]
• Artikelnummer: AMO-M40697
• Hersteller Artikelnummer: M40697
• Alternativnummer: AMO-M40697-1MG,AMO-M40697-5MG,AMO-M40697-10MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: BTK-IN-24

Produktbeschreibung

NX-5948 (BTK-IN-24) is an orally active, blood-brain barrier-penetrating, BTK-targeting degradation agent for the study of B-cell malignancies and autoimmune diseases. NX-5948 induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation.

Produkteigenschaften

• Molekulargewicht: 806.96
• Reinheit: >99.0%
• CAS Nummer: [2649400-34-8]
• Formel: C42H54N12O5
• Target-Kategorie: PROTAC