IAG933 is a first-in-class, selective and orally efficacious YAP1/WWTR1(TAZ)-panTEAD protein-protein interaction inhibitor. IAG933 specifically abrogates the interaction between YAP/TAZ coactivators and all four TEAD isoforms, thus selectively inhibiting TEAD-driven transcriptional activity and inducing anti-cancer effects.
Molekulargewicht:
529.96
Reinheit:
>99.0%
CAS Nummer:
[2714434-21-4]
Formel:
C27H26ClF2N3O4
Target-Kategorie:
YAP
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