TEI-9647 is a Vitamin D3 Lactone analogue, and it is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 blocks both 1alpha,25(OH)2D3-mediated HL-60 cell differentiation and also activation of the luciferase reporter in COS-7 cells that has been transfected with the cDNA containing the DRE of the rat 25(OH)D3-24-hydroxylase gene and cDNA of the human vitamin D nuclear receptor.
Molekulargewicht:
426.59
Reinheit:
>99.0%
CAS Nummer:
[173388-20-0]
Formel:
C27H38O4
Target-Kategorie:
Vitamin
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