BC-1215, CAS [[1507370-20-8]]

Produktübersicht

• Artikelname: BC-1215, CAS [[1507370-20-8]]
• Artikelnummer: AMO-M57279
• Hersteller Artikelnummer: M57279
• Alternativnummer: AMO-M57279-1MG,AMO-M57279-5MG,AMO-M57279-10MG,AMO-M57279-25MG,AMO-M57279-50MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: BC1215

Produktbeschreibung

BC-1215 is a novel inhibitor of F-box protein 3 (Fbxo3) activity. BC-1215 works by antagonizing of Fbxo3 on TRAF cytokine signaling and exhibits a low IC50 in vitro. BC-1215 relieves allodynia by preventing ubiquitination-dependent Fbxl2/TRAF2/TNIK/pGluR1 signaling. BC-1215 exerted robust therapeutic effects in cytokine-driven inflammation, including pseudomona-induced lung injury and cecum ligation/punctured-induced sepsis, by targeting Fbxo3/Fbxl2/TRAF-mediated cytokine release. BC-1215 can be used for the research of inflammation.

Produkteigenschaften

• Molekulargewicht: 394.51
• Reinheit: >99.0%
• CAS Nummer: [1507370-20-8]
• Formel: C26H26N4
• Target-Kategorie: Ligand for E3 Ligase