NBN Antibody - middle region

Produktübersicht

• Artikelname: NBN Antibody - middle region
• Artikelnummer: ASB-ARP30384_T100
• Hersteller Artikelnummer: ARP30384_T100
• Alternativnummer: ASB-ARP30384_T100-25UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human NBN
• Alternative Synonym: ATV, NBS, P95, NBS1, AT-V1, AT-V2

Produktbeschreibung

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1.0 mg/ml
• Molekulargewicht: 85kDa
• NCBI: 4683
• UniProt: O60934
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.