ILK Antibody - C-terminal region

Produktübersicht

• Artikelname: ILK Antibody - C-terminal region
• Artikelnummer: ASB-ARP30445_P050
• Hersteller Artikelnummer: ARP30445_P050
• Alternativnummer: ASB-ARP30445_P050-25UL,ASB-ARP30445_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ILK
• Alternative Synonym: P59, ILK-1, ILK-2, p59ILK, HEL-S-28

Produktbeschreibung

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 49kDa
• NCBI: 3611
• UniProt: Q13418
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.