HNF4A Antibody - N-terminal region

Produktübersicht

• Artikelname: HNF4A Antibody - N-terminal region
• Artikelnummer: ASB-ARP31946_P050
• Hersteller Artikelnummer: ARP31946_P050
• Alternativnummer: ASB-ARP31946_P050-25UL,ASB-ARP31946_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HNF4A
• Alternative Synonym: TCF, HNF4, MODY, FRTS4, MODY1, NR2A1, TCF14, HNF4a7, HNF4a8, HNF4a9, NR2A21, HNF4alpha

Produktbeschreibung

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 53kDa
• NCBI: 3172
• UniProt: P41235
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Host: Rat
Target Name: HNF4A
Sample Tissue: Rat Skeletal Muscle
Antibody Dilution: 1ug/ml

25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Several isoforms contain the peptide sequence in the range of 57 kDa to 46 kDa, and the protein may be ubiquitinated as well as phosphorylated.

WB Suggested Anti-HNF4A Antibody Titration: 0.2-1 ug/ml.A: - blocking peptide.B: + blocking peptide.

Host: Rabbit
Target Name: HNF4A
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml

WB Suggested Anti-HNF4A antibody Titration: 1 ug/mL
Sample Type: Human Liver

Host: Rabbit
Target Name: HNF4A
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: HNF4A
Sample Tissue: Human Lung Tumor
Antibody Dilution: 1.0ug/ml

HNF4A Antibody - N-terminal region (ARP31946_P050) in Rat Skeletal Muscle using Western Blot