TBX21 Antibody - middle region

Produktübersicht

• Artikelname: TBX21 Antibody - middle region
• Artikelnummer: ASB-ARP32612_P050
• Hersteller Artikelnummer: ARP32612_P050
• Alternativnummer: ASB-ARP32612_P050-25UL,ASB-ARP32612_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX21
• Alternative Synonym: TBET, T-PET, T-bet, TBLYM

Produktbeschreibung

TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 58 kDa
• NCBI: 30009
• UniProt: Q9UL17
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Human kidney

Human Skeletal Muscle

WB Suggested Anti-TBX21 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Liver

Host: Rabbit
Target Name: TBX21
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 3ug/ml

Surface Plasmon Resonance Kinetic Characterization of Polyclonal Antibody Affinity. Purified polyclonal antibodies were immobilized on a Protein A/G coated Carterra LSA sensor chip (PAGH200M) at concentrations of 5, and 50 ug/mL in duplicate. Antibodies on the surface were exposed to interaction with peptides sequentially via microfluidic controlled flow at 333nM peptide concentration for kinetic characterization of the binders for affinity and specificity, followed by curve fitting using the Kinetics software. Kd determinations for both concentrations were averaged and results and standard deviation are shown.

TBX21 antibody - middle region (ARP32612_P050) in Human Liver using Western Blot