ARID4A antibody - C-terminal region (ARP33088_T100), Rabbit, Polyclonal

Produktübersicht

• Artikelname: ARID4A antibody - C-terminal region (ARP33088_T100), Rabbit, Polyclonal
• Artikelnummer: ASB-ARP33088_T100
• Hersteller Artikelnummer: ARP33088_T100
• Alternativnummer: ASB-ARP33088_T100-100UL, ASB-ARP33088_T100-25UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ARID4A
• Alternative Synonym: RBP1, RBBP1, RBP-1, RBBP-1

Produktbeschreibung

ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1.0 mg/ml
• Molekulargewicht: 143kDa
• NCBI: 5926
• UniProt: P29374
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.