MMP9 antibody - N-terminal region (ARP33090_T100), Rabbit, Polyclonal

Produktübersicht

• Artikelname: MMP9 antibody - N-terminal region (ARP33090_T100), Rabbit, Polyclonal
• Artikelnummer: ASB-ARP33090_T100
• Hersteller Artikelnummer: ARP33090_T100
• Alternativnummer: ASB-ARP33090_T100-100UL, ASB-ARP33090_T100-25UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MMP9
• Alternative Synonym: GELB, CLG4B, MMP-9, MANDP2

Produktbeschreibung

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1.0 mg/ml
• Molekulargewicht: 78 kDa
• NCBI: 4318
• UniProt: P14780
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.