MMP9 Antibody - N-terminal region

Artikelnummer: ASB-ARP33090_T100
Artikelname: MMP9 Antibody - N-terminal region
Artikelnummer: ASB-ARP33090_T100
Hersteller Artikelnummer: ARP33090_T100
Alternativnummer: ASB-ARP33090_T100-25UL,ASB-ARP33090_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MMP9
Alternative Synonym: GELB, CLG4B, MMP-9, MANDP2
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 78 kDa
NCBI: 4318
UniProt: P14780
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
MMP9 in humanprostate cancer was detected using HRP/AEC red color stain.
Dilution : 2-15 ug/mL
WB Suggested Anti-MMP9 Antibody Titration: 1.25ug/ml
Positive Control: K562 cell lysate
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 4 ug/mL of the antibody was used in this experiment. Recommended dilution for this antibody is 1-3 ug/mL. MMP9 is cleaved from 78 kDa to an approximately 66 kDa mature form.
Host: Rabbit
Target Name: MMP9
Sample Tissue: Human Ovary Tumor
Antibody Dilution: 1ug/ml
Host: Rabbit
Target Name: MMP9
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml
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