PLP1 Antibody - N-terminal region

Produktübersicht

• Artikelname: PLP1 Antibody - N-terminal region
• Artikelnummer: ASB-ARP33843_P050
• Hersteller Artikelnummer: ARP33843_P050
• Alternativnummer: ASB-ARP33843_P050-25UL,ASB-ARP33843_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLP1
• Alternative Synonym: PLP, PMD, HLD1, MMPL, SPG2, GPM6C, PLP/DM20

Produktbeschreibung

PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5 UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5 UTRs, have been identified for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 30kDa
• NCBI: 5354
• UniProt: P60201
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Brain, cerebellum

WB Suggested Anti-PLP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 721_B cell lysate

Host: Mouse
Target Name: PLP1
Sample Tissue: Mouse Spleen
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: PLP1
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: PLP1
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 3ug/ml

Host: Rabbit
Target Name: PLP1
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 3ug/ml

Host: Rabbit
Target Name: PLP1
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 0.5ug/ml

PLP1 antibody - N-terminal region (ARP33843_P050) in Human 721_B using Western Blot