PCSK1 Antibody - middle region
Artikelnummer:
ASB-ARP33848_P050
- Bilder (6)
| Artikelname: | PCSK1 Antibody - middle region |
| Artikelnummer: | ASB-ARP33848_P050 |
| Hersteller Artikelnummer: | ARP33848_P050 |
| Alternativnummer: | ASB-ARP33848_P050-25UL,ASB-ARP33848_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human PCSK1 |
| Alternative Synonym: | PC1, PC3, NEC1, SPC3, BMIQ12 |
| PCSK1 is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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Immunohistochemistry with Pancreas tissue at an antibody concentration of 5ug/ml using anti-PCSK1 antibody (ARP33848_P050) |
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WB Suggested Anti-PCSK1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Small Intestine |
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Host: Rabbit Target Name: PCSK1 Sample Tissue: Human Jurkat Whole Cell Antibody Dilution: 3ug/ml |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The protein may be modified by glycosylation. |
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Host: Rabbit Target Name: PCSK1 Sample Tissue: Human PANC1 Whole Cell Antibody Dilution: 1ug/ml |
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PCSK1 antibody - middle region (ARP33848_P050) in Human Small Intestine using Western Blot |
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