Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human G22P1
Alternative Synonym:
ML8, KU70, TLAA, CTC75, CTCBF, G22P1
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
WB Suggested Anti-G22P1 Antibody Titration: 0.6ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysateXRCC6 is supported by BioGPS gene expression data to be expressed in HepG2
G22P1 antibody - N-terminal region (ARP34117_T100) in Human HepG2 using Western Blot
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