YBX1 Antibody - middle region

Produktübersicht

• Artikelname: YBX1 Antibody - middle region
• Artikelnummer: ASB-ARP34396_P050
• Hersteller Artikelnummer: ARP34396_P050
• Alternativnummer: ASB-ARP34396_P050-25UL,ASB-ARP34396_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human YBX1
• Konjugation: Unconjugated
• Alternative Synonym: YB1, BP-8, CSDB, DBPB, YB-1, CBF-A, CSDA2, EFI-A, NSEP1, NSEP-1, MDR-NF1

Produktbeschreibung

YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. YBX1 binds and stabilizes cytoplasmic mRNA. YBX1 contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. YBX1 binds to promoters that contain a Y-box (5-CTGATTGGCCAA-3), such as HLA class II genes. YBX1 regulates the transcription of numerous genes. YBX1 promotes separation of DNA strands that contain mismatches or are modified by cisplatin. YBX1 has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). YBX1 may play a role in DNA repair. YBX1 is the component of the CRD-mediated complex that promotes MYC mRNA stability.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 36kDa
• NCBI: 4904
• UniProt: P67809
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Placenta

WB Suggested Anti-YBX1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Spleen

YBX1 antibody - middle region (ARP34396_P050) validated by WB using 1. Human NT-2 cells (60ug) at 2ug/ml.

WB Suggested Anti-YBX1 Antibody
Positive Control: Lane 1: 5ug mouse brain cytoplasm Lane 2: 5ug mouse brain nucleus
Primary Antibody Dilution : 1:1000
Secondary Antibody : Anti rabbit - IR-dye
Secondry Antibody Dilution : 1:10,000
Submitted by: Anonymous

YBX1 antibody - middle region (ARP34396_P050) in Human Spleen using Western Blot