The immunogen is a synthetic peptide directed towards the C terminal region of human SCNN1B
Alternative Synonym:
BESC1, ENaCb, SCNEB, LIDLS1, ENaCbeta
When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.