KCNQ2 Antibody - N-terminal region

Produktübersicht

• Artikelname: KCNQ2 Antibody - N-terminal region
• Artikelnummer: ASB-ARP35458_P050
• Hersteller Artikelnummer: ARP35458_P050
• Alternativnummer: ASB-ARP35458_P050-25UL,ASB-ARP35458_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNQ2
• Alternative Synonym: EBN, BFNC, DEE7, EBN1, ENB1, HNSPC, KV7.2, KCNA11

Produktbeschreibung

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 44kDa
• NCBI: 3785
• UniProt: Q53Y30
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Lanes:
100 ug CHO cell lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Goat anti-rabbit HRP
Secondary Antibody Dilution:
1:25000
Gene Name:
KCNQ2
Submitted by:
Anonymous

Immunohistochemistry with Brain, cortex tissue at an antibody concentration of 5ug/ml using anti-KCNQ2 antibody (ARP35458_P050)

WB Suggested Anti-KCNQ2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate

Host: Mouse
Target Name: KCNQ2
Sample Tissue: Mouse Pancreas
Antibody Dilution: 1ug/ml

KCNQ2 antibody - N-terminal region (ARP35458_P050) in Hamster using Western Blot