ZIC2 Antibody - C-terminal region

Produktübersicht

• Artikelname: ZIC2 Antibody - C-terminal region
• Artikelnummer: ASB-ARP35821_P050
• Hersteller Artikelnummer: ARP35821_P050
• Alternativnummer: ASB-ARP35821_P050-25UL,ASB-ARP35821_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, IP, WB
• Spezies Reaktivität: Guinea pig, Human, Mouse, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ZIC2
• Alternative Synonym: HPE5

Produktbeschreibung

ZIC2 is a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects.This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 55kDa
• NCBI: 7546
• UniProt: O95409
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Human Skin

ZIC2 was immunoprecipitated from 1 mg HEK293 Whole Cell Lysate with ARP35821_P050 with 1:200 dilution. Western blot was performed using ARP35821_P050 at 1/1000 dilution.
Lane 1: Control IP in HEK293 Whole Cell Lysate.
Lane 2: ZIC2 IP with ARP35821_P050 in HEK293 Whole Cell Lysate.
Lane 3: Input of HEK293 Whole Cell Lysate.

WB Suggested Anti-ZIC2 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate

Host: Rabbit
Target Name: ZIC2
Sample Tissue: Human HT1080 Whole Cell
Antibody Dilution: 1ug/ml

ZIC2 antibody - C-terminal region (ARP35821_P050) in Human HepG2 using Western Blot