ESR2 Antibody - N-terminal region
Artikelnummer:
ASB-ARP35863_P050
- Bilder (0)
| Artikelname: | ESR2 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP35863_P050 |
| Hersteller Artikelnummer: | ARP35863_P050 |
| Alternativnummer: | ASB-ARP35863_P050-25UL,ASB-ARP35863_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Human, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human ESR2 |
| Alternative Synonym: | Erb, ESRB, ODG8, ESTRB, NR3A2, ER-BETA, ESR-BETA |
| ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. It contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. |
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