NKRF Antibody - N-terminal region

Produktübersicht

• Artikelname: NKRF Antibody - N-terminal region
• Artikelnummer: ASB-ARP35929_P050
• Hersteller Artikelnummer: ARP35929_P050
• Alternativnummer: ASB-ARP35929_P050-25UL,ASB-ARP35929_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NKRF
• Alternative Synonym: NRF, ITBA4

Produktbeschreibung

This protein Interacts with a specific negative regulatory element (NRE) 5-AATTCCTCTGA-3 to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcriptionThis gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 78kDa
• NCBI: 55922
• UniProt: A3F768
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.