SMC1A Antibody - C-terminal region
Artikelnummer:
ASB-ARP38780_P050
- Bilder (5)
| Artikelname: | SMC1A Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP38780_P050 |
| Hersteller Artikelnummer: | ARP38780_P050 |
| Alternativnummer: | ASB-ARP38780_P050-25UL,ASB-ARP38780_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human SMC1A |
| Alternative Synonym: | SMC1, SMCB, CDLS2, DEE85, SB1.8, EIEE85, SMC1L1, DXS423E, SMC1alpha |
| The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by SMC1A gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the SMC1A protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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Rabbit Anti-SMC1A Antibody Catalog Number: ARP38780_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-SMC1A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 293T cell lysateSMC1A is supported by BioGPS gene expression data to be expressed in HEK293T |
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Host: Rabbit Target Name: SMC1A Sample Type: Human HepG2 Antibody Dilution: 1.0ug/mlSMC1A is supported by BioGPS gene expression data to be expressed in HepG2 |
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Host: Rabbit Target Name: SMC1A Sample Type: Human Jurkat Antibody Dilution: 1.0ug/mlSMC1A is supported by BioGPS gene expression data to be expressed in Jurkat |
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SMC1A antibody - C-terminal region (ARP38780_P050) in Human 293T using Western Blot |
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