The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
WB Suggested Anti-KAT5 Antibody Titration: 1.0 ug/ml Positive Control: HT1080 Whole CellThere is BioGPS gene expression data showing that KAT5 is expressed in HT1080