STAT1 Antibody - C-terminal region

Produktübersicht

• Artikelname: STAT1 Antibody - C-terminal region
• Artikelnummer: ASB-ARP38934_P050
• Hersteller Artikelnummer: ARP38934_P050
• Alternativnummer: ASB-ARP38934_P050-25UL,ASB-ARP38934_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human STAT1
• Alternative Synonym: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91

Produktbeschreibung

STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.Western blots using four different antibodies against three unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 87kDa
• NCBI: 6772
• UniProt: P42224
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Rabbit Anti-STAT1 Antibody
Catalog Number: ARP38934_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in hepatocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-STAT1 Antibody Titration: 0.0625ug/ml
Positive Control: Recombinant STAT1 protein

Host: Mouse
Target Name: STAT1
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml

STAT1 antibody - C-terminal region (ARP38934_P050) in Recombinant STAT1 protein using Western Blot