IKZF3 Antibody - N-terminal region

Produktübersicht

• Artikelname: IKZF3 Antibody - N-terminal region
• Artikelnummer: ASB-ARP39004_P050
• Hersteller Artikelnummer: ARP39004_P050
• Alternativnummer: ASB-ARP39004_P050-25UL,ASB-ARP39004_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IKZF3
• Alternative Synonym: AIO, AIOLOS, ZNFN1A3

Produktbeschreibung

IKZF3 is a member of the Ikaros family of zinc-finger proteins. It is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 52kDa
• NCBI: 22806
• UniProt: Q9UKT9-2
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Human Liver

WB Suggested Anti-IKZF3 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate

Host: Rabbit
Target Name: IKZF3
Sample Tissue: Human 786-0
Antibody Dilution: 1.0ug/ml

IKZF3 antibody - N-terminal region (ARP39004_P050) in Human 786-0 using Western Blot