The immunogen is a synthetic peptide directed towards the C-terminal region of Human MXD3
Alternative Synonym:
MYX, MAD3, BHLHC13
MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5-CAC[GA]TG-3. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.