PRMT2 Antibody - N-terminal region

Artikelnummer: ASB-ARP40196_T100
Artikelname: PRMT2 Antibody - N-terminal region
Artikelnummer: ASB-ARP40196_T100
Hersteller Artikelnummer: ARP40196_T100
Alternativnummer: ASB-ARP40196_T100-25UL,ASB-ARP40196_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRMT2
Alternative Synonym: HRMT1L1
The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis and it exerts this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, increasing nuclear IkappaB-alpha and decreasing NF-kappaB DNA binding. PRMT2 also rendered cells susceptible to apoptosis by cytokines or cytotoxic drugs, likely due to its effects on NF-kappaB.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 48kDa
NCBI: 3275
UniProt: P55345
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PRMT2 Antibody
Catalog Number: ARP40196
Paraffin Embedded Tissue: Human Liver
Cellular Data: Liver cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Rabbit Anti-PRMT2 Antibody
Catalog Number: ARP40196
Paraffin Embedded Tissue: Human cardiac cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
WB Suggested Anti-PRMT2 Antibody Titration: 0.625ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
PRMT2 antibody - N-terminal region (ARP40196_T100) validated by WB using human LCL and mouse brains at 1:1000.
PRMT2 antibody - N-terminal region (ARP40196_T100) in Human Jurkat using Western Blot