SSB Antibody - N-terminal region, Rabbit, Polyclonal

Artikelnummer: ASB-ARP40462_P050
Artikelname: SSB Antibody - N-terminal region, Rabbit, Polyclonal
Artikelnummer: ASB-ARP40462_P050
Hersteller Artikelnummer: ARP40462_P050
Alternativnummer: ASB-ARP40462_P050-25UL,ASB-ARP40462_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SSB
Alternative Synonym: La, LARP3, La/SSB
SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE, MIM 152700) (Teplova et al., 2006).[supplied by OMIM].
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 45kDa
NCBI: 6741
UniProt: P05455
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.