KHSRP Antibody - middle region, Rabbit, Polyclonal

Artikelnummer: ASB-ARP40474_P050
Artikelname: KHSRP Antibody - middle region, Rabbit, Polyclonal
Artikelnummer: ASB-ARP40474_P050
Hersteller Artikelnummer: ARP40474_P050
Alternativnummer: ASB-ARP40474_P050-25UL,ASB-ARP40474_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human KHSRP
Alternative Synonym: p75, FBP2, KSRP, FUBP2
KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE).It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 73kDa
NCBI: 8570
UniProt: Q92945
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.