MMP3 Antibody - middle region

Produktübersicht

• Artikelname: MMP3 Antibody - middle region
• Artikelnummer: ASB-ARP42042_P050
• Hersteller Artikelnummer: ARP42042_P050
• Alternativnummer: ASB-ARP42042_P050-25UL,ASB-ARP42042_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MMP3
• Alternative Synonym: SL-1, STMY, STR1, CHDS6, MMP-3, STMY1

Produktbeschreibung

MMP3 can degrade fibronectin, laminin, gelatins of type I, III, IV, and V, collagens III, IV, X, and IX, and cartilage proteoglycans. MMP3 activates procollagenase.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 43kDa
• NCBI: 4314
• UniProt: P08254
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Application: IHC
Species+tissue/cell type: Control-Human small intestine, Sample-human colorectal cancer
Primary antibody dilution: 1:100
Secondary antibody: Biotinylated pig anti-rabbit+streptavidin-HRP

WB Suggested Anti-MMP3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate

MMP3 antibody - middle region (ARP42042_P050) validated by WB using Equine Cartilage Explants at 1:1000.

Sample Type: Equine Cartilage Explants
Primary Dilution: 1:1000
Secondary: Abcam ab97200 (Dilution: 1:20,000)

MMP3 antibody - middle region (ARP42042_P050) in Human Jurkat using Western Blot