COX4I1 Antibody - N-terminal region
Artikelnummer:
ASB-ARP42784_T100
- Bilder (8)
| Artikelname: | COX4I1 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP42784_T100 |
| Hersteller Artikelnummer: | ARP42784_T100 |
| Alternativnummer: | ASB-ARP42784_T100-25UL,ASB-ARP42784_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, IP, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human COX4I1 |
| Alternative Synonym: | COX4, COXIV, COX4-1, COXIV-1, MC4DN16, COX IV-1 |
| Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4I1 is the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3 of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. |
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Human Heart |
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Human kidney |
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Rabbit Anti-COX4I1 Antibody Catalog Number: ARP42784 Paraffin Embedded Tissue: Human cardiac cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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WB Suggested Anti-COX4I1 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysateCOX4I1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells |
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COX4I1 antibody - N-terminal region (ARP42784_T100) validated by WB using 1. Human liver 2. Rat liver 3. Wild-type mouse liver 4. AMPKa1+2-/- mouse liver 5. Human muscle 6. Rat muscle 7. Mouse muscle at 1:1000. |
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Lanes: Lane 1: 50ug HeLa lysate Lane 2: 50ug 293T lysate Lane 3: 50ug K562 lysate Lane 4: 50ug MDA-MB-231 lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:1000 Gene Name: COX4I1 Submitted by: David Colecchia, Ph.D, Istituto Toscano Tumori, Core Research Laboratory, presso Fondazione Toscana Life Sciences |
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COX4I1 was immunoprecipitated from 2 mg HEK293 Whole Cell Lysate with ARP42784_T100 with 1:200 dilution. Western blot was performed using ARP42784_T100 at 1/1000 dilution. Lane 1: Control IP in HEK293 Whole Cell Lysate. Lane 2: COX4I1 IP with ARP42784_T100 in HEK293 Whole Cell Lysate. Lane 3: Input of HEK293 Whole Cell Lysate. |
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COX4I1 antibody - N-terminal region (ARP42784_T100) in Human HepG2 using Western Blot |
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