HDAC9 Antibody - C-terminal region

Produktübersicht

• Artikelname: HDAC9 Antibody - C-terminal region
• Artikelnummer: ASB-ARP42788_T100
• Hersteller Artikelnummer: ARP42788_T100
• Alternativnummer: ASB-ARP42788_T100-25UL,ASB-ARP42788_T100-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: ChIP, IHC, WB
• Spezies Reaktivität: Guinea pig, Human, Mouse, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC9
• Alternative Synonym: HD7, HD9, HD7b, HDAC, HDRP, MITR, HDAC7, HDAC7B, HDAC9B, HDAC9FL

Produktbeschreibung

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC9 has sequence homology to members of the histone deacetylase family. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 may play a role in hematopoiesis.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1.0 mg/ml
• Molekulargewicht: 65 kDa
• NCBI: 9734
• UniProt: Q9UKV0-3, Q9UKV0-8, Q9UKV0-9, Q9UKV0-10, Q9UKV0-11
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Chromatin Immunoprecipitation (ChIP) Using HDAC9 antibody - C-terminal region (ARP42788_T100) and HCT116 Cells

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The c-terminal peptide used to generate this antibody is not present in the full length canonical isoform, but is present in several HDAC9 isoforms below 654 amino acids. In these samples, isoform 8 of 65 kDa is recognized as well as possibly isoform 11 at 57 kDa.

Human kidney

Rabbit Anti-HDAC9 Antibody
Catalog Number: ARP42788
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

WB Suggested Anti-HDAC9 Antibody Titration: 1.25ug/ml
Positive Control: A172 cell lysateHDAC9 is supported by BioGPS gene expression data to be expressed in A172

Host: Rabbit
Target Name: HDAC9
Sample Tissue: Human Fetal Brain
Antibody Dilution: 1.0ug/ml

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