Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB
Alternative Synonym:
NMB, HGFIN, PLCA3
GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly me