ESR1 Antibody - middle region

Artikelnummer: ASB-ARP45592_P050
Artikelname: ESR1 Antibody - middle region
Artikelnummer: ASB-ARP45592_P050
Hersteller Artikelnummer: ARP45592_P050
Alternativnummer: ASB-ARP45592_P050-25UL,ASB-ARP45592_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Human, Porcine, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ESR1
Alternative Synonym: ER, ESR, Era, ESRA, ESTRR, NR3A1
Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision and boundary formation. HEY genes are direct transcriptional targets of the Notch signaling pathways in Drosophila and vertebrates. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5 UTRs and use different promoters.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 66kDa
NCBI: 2099
UniProt: P03372
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-ESR1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate
Host: Rabbit
Target Name: ESR1
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml
Host: Rabbit
Target Name: ESR1
Sample Type: Human Fetal Muscle
Antibody Dilution: 1.0ug/ml
ESR1 antibody - middle region (ARP45592_P050) in Human HeLa using Western Blot