RORC Antibody - N-terminal region

Artikelnummer: ASB-ARP45622_P050
Artikelname: RORC Antibody - N-terminal region
Artikelnummer: ASB-ARP45622_P050
Hersteller Artikelnummer: ARP45622_P050
Alternativnummer: ASB-ARP45622_P050-25UL,ASB-ARP45622_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IF, IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RORC
Alternative Synonym: TOR, RORG, RZRG, IMD42, NR1F3, RZR-GAMMA
RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 58 kDa
NCBI: 6097
UniProt: Q5SZR9
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Anti-ROR Gamma antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ROR Gamma antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Host: Rabbit
Target: RORC
Positive control (+): Human lung (LU)
Negative control (-): HepG2 (HG)
Antibody concentration: 1ug/ml
WB Suggested Anti-RORC Antibody Titration: 1 ug/ml
Positive Control: HepG2 cell lysate
25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.
Host: Rabbit
Target Name: RORC
Sample Tissue: Human MCF7 Whole Cell
Antibody Dilution: 1ug/ml
Host: Rabbit
Target Name: RORC
Sample Tissue: Human Lung Tumor
Antibody Dilution: 3ug/ml
RORC Antibody - N-terminal region (ARP45622_P050) in Human lung, HepG2 using Western Blot