SPTLC1 Antibody - middle region
Artikelnummer:
ASB-ARP46721_P050
- Bilder (4)
| Artikelname: | SPTLC1 Antibody - middle region |
| Artikelnummer: | ASB-ARP46721_P050 |
| Hersteller Artikelnummer: | ARP46721_P050 |
| Alternativnummer: | ASB-ARP46721_P050-25UL,ASB-ARP46721_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human SPTLC1 |
| Alternative Synonym: | HSN1, LBC1, LCB1, SPT1, SPTI, HSAN1 |
| Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. |
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Human kidney |
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WB Suggested Anti-SPTLC1 Antibody Titration: 0.5ug/ml Positive Control: HepG2 cell lysate |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. |
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SPTLC1 antibody - middle region (ARP46721_P050) in Human HepG2 using Western Blot |
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