NOX1 Antibody - C-terminal region

Produktübersicht

• Artikelname: NOX1 Antibody - C-terminal region
• Artikelnummer: ASB-ARP46818_P050
• Hersteller Artikelnummer: ARP46818_P050
• Alternativnummer: ASB-ARP46818_P050-25UL,ASB-ARP46818_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NOX1
• Alternative Synonym: MOX1, NOH1, NOH-1, GP91-2

Produktbeschreibung

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. The NOH-1S currents were reversibly blocked by zinc, a known H+ channel inhibitor. The NOH-1S variant does not contain an electron transport chain and it is thought that H+ conductance is its main physiologic function, whereas NOH-1L may conduct H+ ions as part of its electron transport mechanism.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 65 kDa
• NCBI: 27035
• UniProt: Q9Y5S8
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

WB Suggested Anti-NOX1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate

NOX1 antibody - C-terminal region (ARP46818_P050) validated by WB using Epithelial Colorectal Adenocarcinoma CaCO2 at 1:10.

Host: Rabbit
Target Name: NOX1
Sample Tissue: Human MCF7 Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: NOX1
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 1ug/ml

25 ug of the indicated Human whole cell extracts were loaded per well using 12% SDS-PAGE. Membrane was incubated with 3 ug/mL of antibody.

NOX1 antibody - C-terminal region (ARP46818_P050) in Human Jurkat using Western Blot