PCDHB5 Antibody - N-terminal region, Rabbit, Polyclonal
Artikelnummer:
ASB-ARP47179_P050
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| Artikelname: | PCDHB5 Antibody - N-terminal region, Rabbit, Polyclonal |
| Artikelnummer: | ASB-ARP47179_P050 |
| Hersteller Artikelnummer: | ARP47179_P050 |
| Alternativnummer: | ASB-ARP47179_P050-25UL, ASB-ARP47179_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N-terminal region of Human PCDHB5 |
| Alternative Synonym: | PCDH-BETA5 |
| This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3 exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. |
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