MBTPS2 Antibody - N-terminal region, Rabbit, Polyclonal

Produktübersicht

• Artikelname: MBTPS2 Antibody - N-terminal region, Rabbit, Polyclonal
• Artikelnummer: ASB-ARP47191_P050
• Hersteller Artikelnummer: ARP47191_P050
• Alternativnummer: ASB-ARP47191_P050-25UL, ASB-ARP47191_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MBTPS2
• Alternative Synonym: S2P, IFAP, KFSD, OI19, KFSDX, OLMSX, BRESEK

Produktbeschreibung

This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome), IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 57 kDa
• NCBI: 51360
• UniProt: O43462
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.