GALNAC4S-6ST Antibody - middle region, Rabbit, Polyclonal
Artikelnummer:
ASB-ARP47193_P050
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| Artikelname: | GALNAC4S-6ST Antibody - middle region, Rabbit, Polyclonal |
| Artikelnummer: | ASB-ARP47193_P050 |
| Hersteller Artikelnummer: | ARP47193_P050 |
| Alternativnummer: | ASB-ARP47193_P050-25UL, ASB-ARP47193_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human GALNAC4S-6ST |
| Alternative Synonym: | BRAG, GALNAC4S-6ST |
| GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3-phosphoadenosine 5-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression, however such results are unclear in vivo. |
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