The immunogen is a synthetic peptide directed towards the C terminal region of human CLN6
Alternative Synonym:
nclf, CLN4A, HsT18960
CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-CLN6 Antibody Catalog Number: ARP47372_P050 Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue Observed Staining: Cytoplasmic in cell bodies of pinealocytes Primary Antibody Concentration: 1:100 Other Working Concentrations: 1/600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-CLN6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 293T cell lysateCLN6 is supported by BioGPS gene expression data to be expressed in HEK293T
Host: Rabbit Target: CLN6 Positive control (+): MCF7 (N10) Negative control (-): Human stomach (ST) Antibody concentration: 1ug/ml
CLN6 antibody - C-terminal region (ARP47372_P050) in Human 293T using Western Blot
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