TGM2 Antibody - N-terminal region

Produktübersicht

• Artikelname: TGM2 Antibody - N-terminal region
• Artikelnummer: ASB-ARP47472_P050
• Hersteller Artikelnummer: ARP47472_P050
• Alternativnummer: ASB-ARP47472_P050-25UL,ASB-ARP47472_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TGM2
• Alternative Synonym: TGC, tTG, G(h), hTG2, TG(C)

Produktbeschreibung

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, TGM2 is the autoantigen implicated in celiac disease.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 77kDa
• NCBI: 7052
• UniProt: P21980
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

WB Suggested Anti-TGM2 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate

Host: Rabbit
Target Name: TGM2
Sample Tissue: Mouse Skeletal Muscle
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: TGM2
Sample Tissue: Mouse Skeletal Muscle
Antibody Dilution: 1ug/ml

TGM2 antibody - N-terminal region (ARP47472_P050) in Human HepG2 using Western Blot