ARRB2 Antibody - middle region

Produktübersicht

• Artikelname: ARRB2 Antibody - middle region
• Artikelnummer: ASB-ARP48007_P050
• Hersteller Artikelnummer: ARP48007_P050
• Alternativnummer: ASB-ARP48007_P050-25UL,ASB-ARP48007_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARRB2
• Alternative Synonym: ARB2, ARR2, BARR2

Produktbeschreibung

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 46kDa
• NCBI: 409
• UniProt: P32121
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Human Skin

Sample Type: HepG2 cell lysate
Antibody concentration: 1.0 ug/ml
Gel concentration: 12%.ARRB2 is supported by BioGPS gene expression data to be expressed in HepG2

Sample Type:
Lane 1: 20ug mouse left ventricle heart lysate Primary Antibody Dilution:
1:1000 Secondary Antibody:
Anti-rabbit-HRP Secondary Antibody Dilution:
1:5000 Color/Signal Descriptions:
ARRB2 Gene Name:
Kathleen Gabrielson Submitted by:

ARRB2 antibody - middle region (ARP48007_P050) in Human HepG2 using Western Blot