APEH Antibody - N-terminal region
Artikelnummer:
ASB-ARP48181_P050
- Bilder (7)
| Artikelname: | APEH Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP48181_P050 |
| Hersteller Artikelnummer: | ARP48181_P050 |
| Alternativnummer: | ASB-ARP48181_P050-25UL,ASB-ARP48181_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, IP, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human APEH |
| Alternative Synonym: | APH, OPH, AARE, ACPH, D3S48E, D3F15S2, DNF15S2 |
| APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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Rabbit Anti-APEH Antibody Catalog Number: ARP48181_P050 Formalin Fixed Paraffin Embedded Tissue: Human Adult liver Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 a€'' 2.0 sec Protocol located in Reviews and Data. |
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APEH was immunoprecipitated from 2 mg HEK293 Whole Cell Lysate with ARP48181_P050 with 1:200 dilution. Western blot was performed using ARP48181_P050 at 1/1000 dilution. Lane 1: Control IP in HEK293 Whole Cell Lysate. Lane 2: APEH IP with ARP48181_P050 in HEK293 Whole Cell Lysate. Lane 3: Input of HEK293 Whole Cell Lysate. |
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WB Suggested Anti-APEH Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 721_B cell lysateAPEH is supported by BioGPS gene expression data to be expressed in 721_B |
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WB Suggested Anti-APEH antibody Titration: 1 ug/mL Sample Type: Human liver |
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Host: Rabbit Target Name: APEH Sample Tissue: Mouse Brain Antibody Dilution: 1ug/ml |
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Host: Mouse Target Name: APEH Sample Tissue: Mouse Brain Antibody Dilution: 1ug/ml |
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APEH antibody - N-terminal region (ARP48181_P050) in Human 721_B using Western Blot |
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