IDH2 Antibody - middle region

Produktübersicht

• Artikelname: IDH2 Antibody - middle region
• Artikelnummer: ASB-ARP48207_P050
• Hersteller Artikelnummer: ARP48207_P050
• Alternativnummer: ASB-ARP48207_P050-25UL,ASB-ARP48207_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IDH2
• Alternative Synonym: IDH, IDP, IDHM, IDPM, ICD-M, D2HGA2, mNADP-IDH

Produktbeschreibung

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. IDH2 is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex.Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 47kDa
• NCBI: 3418
• UniProt: P48735
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

WB Suggested Anti-IDH2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human Muscle

IDH2 antibody - middle region (ARP48207_P050) validated by WB using Proximal kidney tubules purfied from cortex at 1:1000.

Host: Rabbit
Target Name: IDH2
Sample Tissue: Mouse Small Intestine
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: IDH2
Sample Tissue: Mouse Small Intestine
Antibody Dilution: 1ug/ml

Host: Rabbit
Target: IDH2
Positive control (+): Human heart (HE)
Negative control (-): Human brain (BR)
Antibody concentration: 1ug/ml

IDH2 antibody - middle region (ARP48207_P050) in Human Muscle using Western Blot